George Yancopoulos, Regeneron president and CSO (Brendan McDermid/Reuters/Alamy)

Block­buster fran­chise ex­pands: Re­gen­eron shares spike on new high-dose Eylea da­ta

Re­gen­eron un­veiled a pair of tri­al wins Thurs­day, se­cur­ing a way to un­lock a like­ly ex­ten­sion to its multi­bil­lion-dol­lar Eylea fran­chise and a stock price bump too.

The com­pa­ny un­veiled two non­in­fe­ri­or­i­ty hits on pri­ma­ry end­points in vi­sion gains for a pair of piv­otal tri­als in­ves­ti­gat­ing its high-dose ver­sion of the megablock­buster Eylea with longer, 12- and 16-week dos­ing reg­i­mens (com­pared to a 2 mg ver­sion with an 8-week dos­ing reg­i­men) in pa­tients with di­a­bet­ic mac­u­lar ede­ma (DME) and wet age-re­lat­ed mac­u­lar de­gen­er­a­tion (wAMD).

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