Boost­er bo­nan­za: FDA en­dors­es 'mix-and-match' scheme, and Mod­er­na and J&J too

The FDA late Wednes­day signed off on au­tho­riz­ing the use of het­erol­o­gous — or what FDA calls a “mix and match” of a pri­ma­ry vac­cine se­ries and dif­fer­ent boost­er dos­es — for all cur­rent­ly avail­able Covid-19 vac­cines, in ad­di­tion to sep­a­rate­ly au­tho­riz­ing Mod­er­na and J&J boost­ers.

On the mix-and-match ap­proach, which FDA of­fi­cials in­sist­ed isn’t too con­fus­ing in a press con­fer­ence, the agency of­fered the ex­am­ple of an 18-year-old who re­ceived the J&J shot at least two months ago and may now re­ceive a sin­gle boost­er of the J&J, a half dose of the Mod­er­na, or the Pfiz­er-BioN­Tech boost­er.

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