Boston Biomedical's lead drug fizzles in difficult-to-treat pancreatic cancer
Months after a combination of Celgene’s Abraxane and the chemotherapy gemcitabine stumbled in a pivotal study involving pancreatic cancer patients who had undergone surgical resection, a late-stage study testing Boston Biomedical’s napabucasin in patients with metastatic pancreatic ductal adenocarcinoma — the most common type of pancreatic cancer — has been discontinued.
Pancreatic cancer is relatively rare but notoriously lethal. It is currently the third leading cause of cancer deaths in the United States — and is projected to move into the second slot by 2020, according to the Memorial Sloan Kettering Cancer Center. It is a field littered with drug trial failure.
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