Bristol-Myers hands over $100M in cash for a new fibrosis drug, beefing up NASH focus
It’s not all checkpoints all the time at Bristol-Myers Squibb. The big biotech has been ramping up an ambitious effort in fibrosis and NASH and this morning it’s taking the wraps off another deal in the field, paying $100 million to Japan’s Nitto Denko for an early-stage drug candidate that now becomes part of their portfolio.
The key drug in this package deal is ND-L02-s0201, a siRNA that is designed to inhibit heat shock protein 47. By hitting HSP47, their investigators believe that they can cut the production of collagen that plays a role in fibrosis and NASH, while helping correct at least some of the damage that has already been done to patients.
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