Broad and MIT scientists repurpose hot RNA editing tech as ‘radar’ with uses in cancer and brain research
RNA editing biotechs pitch impermanence. Instead of making lasting changes to the DNA, RNA editors rewrite the intermediate message before it is translated into proteins. And many RNA editing biotechs, such as Shape Therapeutics, Wave Life Sciences, Korro Bio, and appropriately named ADARx Pharmaceuticals, take advantage of machinery already found in the body — ADAR editing.
ADAR editing converts the RNA code from A to I, which is interpreted as a G. While found in humans, it’s a method used much more actively by octopi and squid to drastically change the code of their nervous system proteins.
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