CAR-T shows promise for lupus in mouse study — will it inspire hope in a beleaguered field?
As one antibody after another gets stacked on the growing pile of failed attempts to tackle lupus, scientists are flagging CAR-T therapies — which have done wonders in the cancer space — as a potential one-off treatment for the autoimmune disease, with some impressive mice data now available.
Their preclinical trial, the University of Tennessee Health Science Center researchers wrote in a Science paper, “provided unambiguous confirmation that CAR T cell therapy profoundly affects autoimmune disease progression in both NZB/W and MRL-lpr mice.”
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