Cell therapy player GammaDelta spins off Adaptate to direct body's surveillance system
If alpha beta T-cells — the foundation of CAR-T cell therapy — are “killer cells,” trained in the biologically ancient art of executing intruders, think of their gamma delta cousins as armed guards, capable of engaging an interloper but also of sounding an alarm to kick the rest of the body’s defenses into action.
“The key role they play is to conduct immune surveillance,” Natalie Mount told Endpoints News. And once they find an intruder “they can stimulate a whole immune response as well as be cytotoxic [cell-killing].”
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