Close­ly-watched in­ter­na­tion­al CRISPR ethics pan­el leaves door ajar for germline edit­ing — one day

In 2017, some of the world’s top sci­en­tists and ethi­cists emerged from over a year of de­lib­er­a­tions with a re­port meant to fi­nal­ly lay down guid­ing prin­ci­ples for how CRISPR, the awe­some-pow­er-awe­some-re­spon­si­bil­i­ty genome edit­ing tool, should be safe­ly and moral­ly used.

Then, just months lat­er, a sci­en­tist named He Jiankui an­nounced he had used the tool to ed­it em­bryos and cre­ate so-called “CRISPR ba­bies.” That was baf­fling to the ex­perts who uni­ver­sal­ly preached cau­tion, but so was his next claim: That he had done so while fol­low­ing the — in hind­sight, vague — prin­ci­ples set out in the re­port.

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