Clo­vis shares tank af­ter in­vestors size up the dis­ap­point­ing da­ta on ru­ca­parib

Clo­vis On­col­o­gy’s shares got ham­mered this morn­ing af­ter the biotech re­vealed some mixed re­sults for its PARP in­hibitor ru­ca­parib.

The biotech re­port­ed a 54% ob­jec­tive re­sponse rate for the drug for BR­CA-mu­tat­ed ovar­i­an can­cer, with nine (9%) com­plete re­spon­ders and 48 (45%) par­tial re­spon­ders. Bor­ing down in­to the da­ta, in­ves­ti­ga­tors al­so re­port­ed ze­ro re­sponse among the 7% of the pa­tients who were plat­inum-re­frac­to­ry, a 25% re­sponse rate for plat­inum-re­sis­tant pa­tients and 66% for plat­inum-sen­si­tive re­spons­es.

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