David Liu takes the wraps off $315M launch round for Prime Medicine and new CRISPR tech that gave Bob Nelsen a 'holy crap' moment
Venture capitalist Bob Nelsen was sitting on his couch two summers ago when he got a call from a famous scientist, who matter-of-factly explained that he had developed a potentially groundbreaking technology but that he couldn’t give any details about how it worked.
David Liu, the Harvard biologist known for inventing “CRISPR 2.0,” told Nelsen that he and a postdoc had invented what — though he didn’t use the term — could reasonably be called CRISPR 3.0. The gene editing technology could replace any DNA base with any other. It could delete bases or add them, he said, effectively turning the human genome into a word processor. In theory, nearly 90% of known pathogenic genetic variations could be corrected.
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