Eiger chalks up one win, one loss be­tween a pair of PhII rare dis­ease drugs, reshuf­fling pri­or­i­ties

Months af­ter Eiger Bio­phar­ma­ceu­ti­cals con­ced­ed uben­imex had no ef­fect in pul­monary ar­te­r­i­al hy­per­ten­sion, the drug has proven to be a flop again — this time in low­er leg lym­phede­ma.

When com­pared to place­bo in a Phase II study, pa­tients on uben­imex showed no im­prove­ment in the swelling on their limbs, whether mea­sured by skin thick­ness (pri­ma­ry end­point) nor limb vol­ume and bioim­ped­ance (sec­ondary end­point).

Endpoints News

Unlock this article instantly by becoming a free subscriber.

You’ll get access to free articles each month, plus you can customize what newsletters get delivered to your inbox each week, including breaking news.