FDA or­ders clin­i­cal hold on Aprea's p53 re­ac­ti­va­tor as strug­gling biotech pledges to ad­dress safe­ty con­cerns

Lit­tle Aprea Ther­a­peu­tics just tripped yet again on its rocky path to de­vel­op a drug that can re­ac­ti­vate the mu­tant tu­mor sup­pres­sor pro­tein p53. …

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