Results, RNAi

RNAi trailblazer Alnylam posts promising top-line PhIII snapshot for givosiran, but safety issues drag shares down

Alnylam’s second late-stage RNAi drug just cleared one of the last big hurdles on its way to a possible — maybe even probable — approval at the FDA and EMA for acute hepatic porphyria.

The RNAi trailblazer {$ALNY} offered up a promising assessment of its Phase III pivotal for givosiran — hitting the primary on reducing the annualized rate of composite porphyria attacks compared to placebo with a p value packed with zeroes: 0.00000001.


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Research Scientist - Immunology
Recursion Pharmaceuticals Salt Lake City, UT
Director of Operations
Atlas Venture Cambridge, MA

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