Food-sourced mi­cro­bio­me drugs get $101M megaround for Flag­ship's Kalei­do

Min­ing food for safer sources of chem­istry, mi­cro­bio­me start­up Kalei­do has closed a $101 mil­lion megaround to push its pipeline through the clin­ic.

The com­pa­ny, found­ed by Flag­ship back in 2015, is tack­ling rare ge­net­ic dis­or­ders, meta­bol­ic dis­ease, on­col­o­gy, and oth­er dis­ease tar­gets. And it’s got four pro­grams al­ready in ear­ly-stage clin­i­cal tri­als. Kalei­do says its tri­als are rapid­ly ad­vanc­ing thanks to two fac­tors: its R&D en­gine lets the com­pa­ny study the hu­man mi­cro­bio­me in a lab set­ting, and its com­pound li­brary in­cludes “sources of chem­istry pre­dom­i­nant­ly found in foods, sig­nif­i­cant­ly re­duc­ing safe­ty con­cerns.”

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