From hours to minutes? Genentech says Ocrevus subcutaneous formulation works just as well as IV
To receive Roche’s multiple sclerosis drug Ocrevus, patients currently have to sit through two to four hours of infusion every six months. A year ago, Roche launched a Phase III study to test an idea: Can a new formulation cut down that time to 10 minutes?
New Phase III results suggest the answer is yes, the company reported Thursday.
Without breaking down the numbers, Roche said its Ocrevus subcutaneous injection “was shown to be non-inferior to Ocrevus given by intravenous infusion,” as measured by levels of the drug in the blood over 12 weeks. Looking at magnetic resonance imaging (MRI) lesions activity in the brain, the subcutaneous version was also comparable in keeping the lesions under control — with a consistent safety profile.
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