Gates-backed study of faster tu­ber­cu­lo­sis drug treat­ments kicks off in South Africa

An im­por­tant test of new drugs that aim to treat tu­ber­cu­lo­sis in­fec­tions more ef­fi­cient­ly has be­gun in South Africa.

The Phase II clin­i­cal tri­al, spon­sored by the Bill & Melin­da Gates Med­ical Re­search In­sti­tute, will test five dif­fer­ent an­tibac­te­r­i­al com­pounds across two new drug reg­i­mens in a bid to find a com­bo that short­ens treat­ment times.

Tu­ber­cu­lo­sis is the biggest in­fec­tious dis­ease killer in the world, with rough­ly 10.6 mil­lion new cas­es and 1.6 mil­lion deaths re­port­ed in the most re­cent count in 2021. The cur­rent treat­ment typ­i­cal­ly re­quires gru­el­ing six-month cours­es of mul­ti­ple an­tibi­otics and has seen lit­tle change in near­ly half a cen­tu­ry.

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