Genen­tech I/O chief Dan Chen heads to an up­start biotech look­ing to cre­ate a land­mark ad­vance on an­ti­bod­ies

One of the top sci­en­tif­ic lead­ers be­hind the emer­gence of PD-1/L1 check­point in­hibitors has left Genen­tech to take the chief med­ical of­fi­cer’s job at a low-pro­file biotech up­start look­ing to make an­ti­body his­to­ry.

Dan Chen, who led the de­vel­op­ment of Tecen­triq from start to post-mar­ket star­dom, has tak­en the CMO’s job at IgM Bio­sciences in Moun­tain View, CA.

I couldn’t find much about them. No ven­ture rounds or high-pro­file en­dorse­ments. But the web­site in­cludes some lofty claims about their goal to re­vamp the way an­ti­bod­ies are de­vel­oped, build­ing on a blue­print that can sig­nif­i­cant­ly in­crease the abil­i­ty of an an­ti­body to bind with mul­ti­ple do­mains us­ing a much more com­plex IgM struc­ture, rather than the Ig­Gs that dom­i­nate the in­dus­try.

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