Glax­o­SmithK­line re­thinks strat­e­gy for Covid-19 an­ti­body — not the Vir ones — af­ter tri­al flop. Is there hope in high-risk pa­tients?

In the search for a bet­ter Covid-19 ther­a­peu­tic, Glax­o­SmithK­line and Vir have part­nered up on two an­ti­bod­ies they hope have a chance. GSK is al­so test­ing its own in-house an­ti­body, and ear­ly re­sults may have shut the door on its wide­spread use.

A com­bi­na­tion of GSK’s mon­o­clon­al an­ti­body otil­imab plus stan­dard of care couldn’t best stan­dard of care alone in pre­vent­ing death and res­pi­ra­to­ry fail­ure in hos­pi­tal­ized Covid-19 pa­tients af­ter 28 days, ac­cord­ing to da­ta from the Phase IIa OS­CAR study un­veiled Thurs­day.

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