Al­phaFold, meet Al­phaMis­sense: Google Deep­Mind's AI suc­ces­sor pre­dicts how 71M mu­ta­tions cause dis­ease

Google Deep­Mind has de­vel­oped an AI sys­tem that pre­dicts the chances that tens of mil­lions of ge­net­ic vari­ants will cause dis­ease.

Called Al­phaMis­sense, the tech­nol­o­gy is the high­ly-await­ed fol­low-up to its Al­phaFold, which pre­dict­ed the struc­tures of pro­teins. It was un­veiled in a Sci­ence pa­per pub­lished Tues­day, along with pre­dic­tions on 71 mil­lion so-called mis­sense mu­ta­tions. Each mu­ta­tion is the change of a sin­gle let­ter in an amino acid that makes up a pro­tein se­quence.

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