David Liu (Broad Institute)

In­ter­view with the Broad In­sti­tute's David Liu: Is this the year base edit­ing makes its mark?

For those track­ing the progress of genome edit­ing, the Broad In­sti­tute of Har­vard and MIT’s David Liu like­ly needs no in­tro­duc­tion (Google him for a re­fresh­er), and 2022 might be the year that the edit­ing tech­niques he and his lab cre­at­ed start to make re­al strides in the clin­ic.

Liu’s lab has pi­o­neered two new el­e­gant and pre­cise ways to cut DNA and re­place bases with pre­ci­sion, but with­out mak­ing any of the DNA dou­ble-strand­ed breaks that can some­times lead to off-tar­get ef­fects.

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