Heart­burn: Iron­wood shares sink af­ter block­buster con­tender dis­ap­points on a key goal in PhI­Ib

Iron­wood Phar­ma­ceu­ti­cals $IR­WD CEO Pe­ter Hecht has some block­buster ex­pec­ta­tions for one of his top clin­i­cal can­di­dates. But he’s hav­ing a hard time con­vinc­ing an­a­lysts and in­vestors of that to­day af­ter rolling out a dis­ap­point­ing batch of top-line da­ta.

The biotech re­port­ed Thurs­day morn­ing that the high dose of its ex­per­i­men­tal drug — IW-3718 — for gas­troe­sophageal re­flux dis­ease (GERD) not con­trolled by avail­able meds hit the pri­ma­ry end­point on sig­nif­i­cant­ly re­duc­ing heart­burn sever­i­ty for pa­tients in a Phase IIb tri­al.

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