Iron­wood's for­mer pipeline spin­out hits an­oth­er speed bump, lay­ing off 45% and turn­ing to­ward the mi­to­chon­dria

To the cha­grin of the sec­tor, an­oth­er biotech is con­duct­ing lay­offs Thurs­day while mak­ing a some­what sig­nif­i­cant turn — its sec­ond in the last 24 months.

Boston-area Cy­cle­ri­on Ther­a­peu­tics an­nounced it would slash its staff by 45% as it con­ducts a piv­ot to­ward mi­to­chon­dr­i­al dis­eases. In ad­di­tion to trim­ming the head­count to about 16 em­ploy­ees, ex­ecs plan to out-li­cense and part­ner out a hand­ful of pipeline pro­grams fo­cused on kid­ney and neu­ropsy­chi­atric dis­eases.

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