Jazz re­ports sur­prise PhI­II flop for cannabi­noid drug from $7.2B GW buy­out

In a sur­prise set­back, Jazz Phar­ma­ceu­ti­cals says a cannabi­noid it ac­quired from GW has failed a key Phase III tri­al.

The RE­LEASE MSS1 tri­al, which test­ed nabix­i­mols oro­mu­cos­al spray in pa­tients with mul­ti­ple scle­ro­sis spas­tic­i­ty, did not meet the pri­ma­ry end­point of change in Low­er Limb Mus­cle Tone-6 (LLMT-6) be­tween base­line and Day 21, the com­pa­ny re­port­ed, as mea­sured by the Mod­i­fied Ash­worth Scale.

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