J&J’s stellar prostate cancer data signals the likelihood of a broader market approval, as Pfizer rival struggles
CHICAGO — J&J will be looking to expand its blockbuster market for Zytiga (abiraterone) after posting stellar data at ASCO showing that the drug combined with standard hormone therapy registered a major improvement in progression-free survival among newly diagnosed patients with metastatic prostate cancer.
The LATITUDE study data demonstrated that the combination therapy delivered an average stretch of 33 months without the disease worsening, compared to 14.8 months for standard hormone therapy. Zytiga plus prednisone in combination with ADT decreased the risk of progression or death by 53% compared to placebo plus ADT in patients with mHNPC. And while overall survival was not reached yet for the Zytiga combo, the comparison arm came in at 34.7 months.
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