Michael Shpigelmacher

Khosla joins bet on un­con­ven­tion­al start­up look­ing to send drug de­liv­er­ing ro­bots in­to the brain

When Michael Sh­pigel­mach­er start­ed the project, he knew he’d have to fund it him­self. Every oth­er ef­fort of its kind was aca­d­e­m­ic, re­ject­ed as too risky by in­vestors.

Sh­pigel­mach­er, a ro­bot­ics geek and en­tre­pre­neur who had drift­ed in­to con­sult­ing for phar­ma, want­ed to build the re­al-life equiv­a­lent of tech­nol­o­gy from the 1960s film “Fan­tas­tic Voy­age,” the one where a sub­ma­rine crew is shrunk to “about the size of a mi­crobe” and sent on a mis­sion to re­pair a sci­en­tist’s brain. He scanned the lit­er­a­ture, found the lab that was work­ing on the most ad­vanced project — at the Max Planck In­sti­tute in Ger­many, it turned out — and start­ed fund­ing them with mon­ey from his and his co-founders’ own ac­counts, along with some seed cash from friends and fam­i­ly.

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