Lagging further behind, AstraZeneca adds fresh details to its checkpoint comeback strategy
AstraZeneca has sketched out some fresh details on its mission critical pivotal study on its checkpoint drug approach to non-small cell lung cancer, mapping another likely delay as the pharma giant looks for its first big opening in the megablockbuster cancer market.
The MYSTIC study has been enrolling lung cancer patients regardless of PD-L1 expression status. In its statement today the pharma giant says it will evaluate progression-free survival as well as overall survival for durvalumab combined with tremelimumab — its all-important I/O + I/O matchup that will look to outperform the therapies already approved for frontline and second line patients — for all comers as well as PD-L1 expressers. And it will also now explore the data for durvalumab as a monotherapy.
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