Corrected: Merck KGaA bags another protein degrader deal for $16M upfront, this time with C4
In the latest development in the “highly dynamic” protein degrader space, Merck KGaA has inked a discovery agreement with C4 Therapeutics for two drugs against cancer targets.
C4 will receive $16 million upfront and is eligible for up to $740 million in milestones and tiered royalties on sales ranging from the mid-single to low-double digits, per a company release.
The Watertown, MA-based biotech plans to use its TORPEDO platform to design two candidates targeting undisclosed oncogenic proteins that C4 has progressed within its own discovery pipeline. The German pharma is then set to take the reins on potential clinical development and commercialization.
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