Mi­cro­bio­me, in­flam­ma­tion and mu­ta­tions: US re­searchers win £60M in Can­cer Re­search UK grants to lead 'grand chal­lenges'

Can­cer Re­search UK is putting lead­ing US re­searchers as the faces of its lat­est Grand Chal­lenge — five-year re­search pro­grams that each draw from £20 mil­lion ($25.9 mil­lion) in fund­ing and an in­ter­na­tion­al group of sci­en­tists to tack­le some of the biggest ques­tions in can­cer.

Se­lect­ed from 134 ap­pli­ca­tions in the sec­ond in­stall­ment of the com­pe­ti­tion, the three projects will at­tempt to ma­nip­u­late the mi­cro­bio­me to fight bow­el can­cer, ex­plore the links be­tween chron­ic in­flam­ma­tion and can­cer, and un­der­stand why cer­tain ge­net­ic mu­ta­tions cause can­cer in some tis­sues but not oth­ers.

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