Mirati Therapeutics / Credit: AP Images

Mi­rati team demon­strates that their KRAS G12C drug is ac­tive in NSCLC — but how do they stack up next to Am­gen?

We have our­selves a horse race to watch in KRAS G12C, but it’s go­ing to be aw­ful­ly hard to call at this very ear­ly stage of the com­pe­ti­tion.

Mi­rati — $MRTX led by CEO Chuck Baum — came through with an en­cour­ag­ing set of re­spons­es to re­view for MRTX849 — par­tic­u­lar­ly among a group of 6 evalu­able pa­tients suf­fer­ing from non-small cell lung can­cer who had re­ceived a dose of 600 mg twice dai­ly, which is the high dose they plan to take for­ward as most like­ly to get a re­sponse with the least amount of po­ten­tial harm to the pa­tient.

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