New David Liu study de­tails virus-like de­liv­ery sys­tem for prime edit­ing

Re­searchers led by gene edit­ing pi­o­neer David Liu have de­vel­oped an­oth­er way to de­liv­er prime ed­i­tors and shown that it can be used in mice to de­liv­er a gene edit­ing ther­a­py that par­tial­ly re­stores vi­sion.

The sci­en­tists en­gi­neered virus-like par­ti­cles, which they call eVLPs for short, to de­liv­er all the key parts need­ed for prime edit­ing, ac­cord­ing to the pa­per pub­lished in Na­ture Biotech­nol­o­gy. Virus-like par­ti­cles are com­plex­es made up of vi­ral pro­teins but lack vi­ral ge­net­ic ma­te­r­i­al, so they aren’t in­fec­tious.

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