Novartis, Amgen rack up their first PhIII success in a crowded CGRP migraine drug field
Novartis and its partners at Amgen say that their CGRP migraine drug erenumab (AMG 334) came through in a Phase III study, beating a placebo response in cutting the average number of episodes patients experienced each month. And analysts can now start running the numbers again as they slice and dice the data to see if any of the several rivals in this field can do better.
The two pharma giants enrolled 577 migraine sufferers for the pivotal trial, tracking a baseline of 8 migraine days per month. The patients in the drug arm getting a subcutaneous 70 mg dose one monthly saw that drop an average of 2.9 days, which was significantly better than the 1.8-day drop from a placebo.
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