Novartis axes a once 'first-in-class' prospect as another JAK program fails to clear a risk/benefit analysis
The JAK class can count one more clinical failure, the latest in a long string of setbacks that continues to cloud the future of these therapies.
In its Q4 update today pharma giant Novartis noted that it has swept out a pan-JAK program for CEE321. Details are scant, and the work was very much early-stage, but Novartis had held it up as a bright prospect before for atopic dermatitis.
In their pipeline summary, the company noted that the program had been discontinued because it had failed to clear the bar on risk/benefit.
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