Novartis' CDK4/6 med Kisqali, firmly the sales underdog against Pfizer's Ibrance, drops big OS data
With blockbuster Ibrance from Pfizer in its sights, Novartis pushing hard to build the clinical case for CDK4/6 inhibitor Kisqali with three years on the market. In terms of overall survival, Kisqali just dropped a major win in specific breast cancer patients, and it could help the drug bridge the sales gap.
Adding Novartis’ CDK4/6 inhibitor Kisqali to endocrine therapy gave premenopausal HR-positive, HER2-negative breast cancer patients a median of 11 extra months to live over endocrine therapy alone, marking a 24% death risk reduction, according to Phase III data from the Monaleesa-7 trial unveiled Wednesday at the virtual San Antonio Breast Cancer Symposium.
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