Cyanotriazole binds to the DNA cleavage site of Trypanosoma cruzi Topoisomerase II via a covalent bond with a cysteine residue. (Andreas Schenk)

No­var­tis-led group de­vel­ops new class of an­tipar­a­sitic drug tar­get­ing dis­eases caused by try­panosomes

Try­panosomes look like mi­cro­scop­ic one-celled eels, but in­stead of wa­ter, some of the par­a­sites swim in blood and oth­ers dive in and out of cells …

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