Novo Nordisk's oral semaglutide on par with injectable version in weight loss and safety
An oral version of Novo Nordisk’s semaglutide helped patients taking the highest dose lose 15% of their body weight, the company reported in a new update.
It’s on par with Novo’s Wegovy, which is the injectable version of semaglutide that is approved for weight loss. Obese or overweight patients who took Wegovy lost 15% of their weight from a baseline of 105 kg, according to the FDA label.
In the 68-week Phase III OASIS-1 study, Novo tested out escalating doses up to 50 mg of semaglutide in over 600 patients who are overweight or obese, according to data released at the American Diabetes Association’s annual conference on Sunday night. The study found that participants taking the 50 mg dose saw a 15.1% body weight reduction compared to 2.4% on placebo.
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