Ole­ma gives small up­date to breast can­cer drug at cen­ter of lay­offs, 2021 da­ta leak

Ole­ma Phar­ma­ceu­ti­cals is out with more da­ta on its in­ves­ti­ga­tion­al breast can­cer drug, for which it shed 25% of its work­force two months ago to keep fund­ing its re­search.

The San Fran­cis­co-based biotech said its drug, which was at the cen­ter of a “fal­si­fied” da­ta leak in No­vem­ber 2021, was “well-tol­er­at­ed” and had no dose-lim­it­ing tox­i­c­i­ties when com­bined with Pfiz­er’s Ibrance. Ole­ma is test­ing OP-1250 in pa­tients with ER+/HER2- metasta­t­ic breast can­cer, and the safe­ty and tol­er­a­bil­i­ty up­date comes from a look at 29 pa­tients.

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