Fully synthetic genome nears completion in a step toward unraveling genetic mysteries
An international effort to create yeast cells with a fully synthetic genome is nearing completion, with the eventual aim of unraveling the mysteries of genomes and ushering in a tool for producing complex medicines.
Scientists hope to create the synthetic organism by stitching together small pieces of DNA into artificial chromosomes and trimming out some genetic fat in the process.
The Synthetic Yeast Genome Project — abbreviated Sc2.0 — dates back more than 15 years. Now, in the consortium’s biggest update since revealing five synthetic chromosomes in 2017, its scientists published 10 papers describing the creation of most of the remaining chromosomes, along with a wholly new one that does not exist in nature.
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