Researchers outline another big disease target for Novartis’ canakinumab as drug slashes rate of gout flares
We’ve already seen Novartis’ outline of positive data underscoring canakinumab’s ability to reduce risks for cardio patients by tamping down on the interleukin-1β pathway. Now researchers have also outlined how it may help people suffering from gout.
The data are coming from a secondary analysis of the big CANTOS study, which Novartis is using to make its bid for a potential blockbuster cardio OK. Investigators divvied up patients by low, medium and high scores based on their serum urate level, which triggers painful gout flares. And they found the drug slashed the rate of gout flares by more than half in all three compared to placebo, with a hazard ratio starting at 0.40, then 0.48 and 0.45 for the high group.
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