Researchers plot a course into PhIII after another Alzheimer’s drug flunks a key test
Another big Alzheimer’s drug study has foundered in the clinic, but it’s being positioned for Phase III in any case.
This time the failure belongs to Toyama Chemical, a subsidiary of Fujifilm, which wound up recruiting close to 500 patients with a mild-to-moderate form of the disease for the trial.
According to the company, the drug failed the primary endpoint and the secondaries, proving unable to do any better than a placebo in improving cognition or function. But, researchers say they tracked a benefit in a key biomarker for tau on the high dose while spotting an improvement among earlier-stage patients in a post hoc analysis of the data.
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