Roche is bringing back gantenerumab from the dead, taking another stab at Alzheimer’s PhIII
Alzheimer’s drugs are expensive to test and unlikely to succeed, but they are also hard to kill.
More than two years after gantenerumab failed decisively in treating early-stage Alzheimer’s, Roche is mapping out an attempted comeback through a new, pivotal Phase III program that puts them back into the late-stage pipeline with their second therapy.
Investigators stubbornly vowed back at an international Alzheimer’s conference in 2015 that if you amped up the dosage of the amyloid beta antibody it would be possible to track a real treatment effect for Alzheimer’s, improving cognition and function. And now Roche partner MorphoSys, which contributed its platform tech in discovering the drug, says the pharma giant is going for it — again.
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