Roche punts a PhI cancer drug out of the pipeline and back to Oryzon
Little Oryzon Genomics in Spain picked up a considerable endorsement and financial support when Roche stepped in three years ago to partner on its lysine specific demethylase-1 (LSD1) inhibitor ORY-1001 (RG6016) for acute myloid leukemia and solid tumors. But it had to give up the deal and the $500 million in milestones that came with it after Roche decided to punt it out of the pipeline.
According to Oryzon, the drug didn’t make the cut at the Swiss pharma giant as it “reprioritized” its pipeline. Roche will see through an ongoing Phase I study in small cell lung cancer and then hand it all back to Oryzon, which plans to carry on with the work.
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