Sanofi’s BTK inhibitor from Principia deal succeeds in Phase 3 immune thrombocytopenia trial
Sanofi’s $3.7 billion buyout of Principia Biopharma may be starting to pay off after a covalent BTK inhibitor it obtained in the deal hit the primary endpoint in a Phase 3 test in patients with an autoimmune blood disorder.
The Phase 3 LUNA 3 trial set twice-daily oral rilzabrutinib — which Sanofi acquired during its 2020 purchase of Principia — versus placebo in adults and adolescents with persistent or chronic immune thrombocytopenia (ITP).
Unlock this article instantly by becoming a free subscriber.
You’ll get access to free articles each month, plus you can customize what newsletters get delivered to your inbox each week, including breaking news.