Scientists and startups reveal new gene insertion techniques, though much remains behind closed doors: #ASGCT24
Several secretive and well-funded biotechs are sharing the first glimpses of data from a new suite of gene editing tools that promise to overcome one of the field’s grand challenges: precisely inserting large sequences of DNA, or even whole genes, into the genome.
So far, most work with CRISPR gene editing has used the tool to turn off problematic genes. Newer versions of the technology, like base editing and prime editing, can make small changes to one or a few letters of genetic code, respectively. But replacing large swathes of errant code, or uploading brand new ones, has remained a challenge.
Unlock this article instantly by becoming a free subscriber.
You’ll get access to free articles each month, plus you can customize what newsletters get delivered to your inbox each week, including breaking news.
