Searching for HIV cure, Gilead's new 'shock and kill' combo swats back lethal virus in monkeys
A prominent group of scientific investigators has taken another step toward a possible eventual cure for HIV — one of the longest and most difficult trails in drug R&D — using a combo drug from Gilead.
While combination therapies have long proven able to keep HIV locked into hidden cellular reservoirs, eliminating those viral pockets has proven to be devilishly difficult. In a new animal study involving rhesus monkeys, though, researchers at Harvard working at Beth Israel Deaconess Medical Center advanced a lengthy effort in pursuing a “shock and kill” strategy using a toll-like receptor combined with a killer antibody.
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