Supernus gets a (temporary) boost as ADHD drug clears PhIIb hurdle
Rockville, MD-based Supernus reported positive mid-stage data for one of two top experimental drugs in the pipeline. The biotech says that three doses of SPN-812 — ranging from 200 mg to 400 mg a day — handily beat out a placebo in treating ADHD. But despite an initial jump in the stock price, shares quickly slid south Tuesday morning.
Using the ADHD Rating Scale-IV, investigators tracked baseline score changes of -19.0, -18.6 and -18.4 for the three doses. That compares favorably with the 10.5-point drop for a placebo, hitting the primary endpoint in the study. A 100 mg dose failed to measure up, though.
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