Ver­tex’s pain drug suc­ceeds in late-stage stud­ies, mark­ing ma­jor break­through in search for new, non-opi­oid med­i­cines

An ex­per­i­men­tal non-opi­oid drug low­ered pain lev­els in a se­ries of piv­otal stud­ies, ac­cord­ing to the drug’s de­vel­op­er Ver­tex Phar­ma­ceu­ti­cals, which means a new, non-ad­dic­tive type of pain med­i­cine could soon be on the mar­ket.

In two Phase III stud­ies that each had over 1,000 par­tic­i­pants, those who re­ceived Ver­tex’s pain pill VX-548 af­ter surgery ex­pe­ri­enced a greater re­duc­tion in pain over two days com­pared to those who re­ceived place­bo. Par­tic­i­pants in one study had an ab­domino­plas­ty, known oth­er­wise as a tum­my tuck, and those in the sec­ond had bunion surgery.

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