Siddhartha Mukherjee (Evan Agostini/Invision/AP)

With lessons learned from Vor, Sid­dhartha Mukher­jee takes a dif­fer­ent route to tar­get sol­id tu­mors with start­up Myeloid

Sid­dhartha Mukher­jee is a busy man these days.

The Pulitzer Prize-win­ning au­thor, Co­lum­bia pro­fes­sor, on­col­o­gist, hema­tol­o­gist and lead­ing can­cer re­searcher in 2016 launched Vor, a Cam­bridge, MA-based start­up fo­cused on a new can­cer treat­ment in which cell sur­face anti­gens such as CD33 are re­moved from hematopoi­et­ic stem cells. They can then un­leash a CAR-T ther­a­py — made from T cells in a pa­tient’s blood and ge­net­i­cal­ly en­gi­neered to hunt for the anti­gens — to treat can­cer us­ing the body’s own im­mune sys­tem with­out at­tack­ing healthy cells that would’ve shared those anti­gens.

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