Xy­lo­Cor wraps up PhII for heart dis­ease gene ther­a­py, plans for piv­otal tri­al

Xy­lo­Cor Ther­a­peu­tics says pa­tients with heart dis­ease who got its gene ther­a­py could ex­er­cise for longer and had few­er chest pain at­tacks. The biotech an­nounced it com­plet­ed a Phase I/II tri­al of the gene ther­a­py Thurs­day morn­ing, and plans to move for­ward with a piv­otal tri­al.

In the Phase II por­tion of the tri­al, 28 pa­tients with angi­na (or chest pain) caused by coro­nary artery dis­ease and who had no oth­er treat­ment op­tions were en­rolled and were giv­en the high­est test­ed dose from the first part of the tri­al. Pa­tients were fol­lowed for six months.

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