Moderna expands pipeline to include liver disease programs; Imperial researchers team up with Heptares on gastrointestinal diseases
→ Moderna‘s pipeline now includes 19 mRNA drug candidates, including two new liver disease programs and 10 drugs in the clinic. New programs include mRNA-3927, for a rare disease within the liver modality, and mRNA-1944, which directs liver expression of an antibody that might neutralize chikungunya virus circulating in the blood. The company’s product candidates span infectious diseases, immuno-oncology, rare diseases and cardiovascular diseases. “We have achieved critical milestones in R&D, having gone from four clinical programs at the beginning of the year to now having 10 medicines in human testing, and our intention is to continue to rapidly advance our pipeline with an array of new development programs,” said Moderna’s CEO Stéphane Bancel in a statement. “2016 was the year of mRNA vaccines in the clinic. 2017 was the year of several mRNA therapeutics in the clinic. In 2018, we will continue to evolve our pipeline of mRNA therapeutics, specifically focusing on discovering new rare disease drug candidates, while remaining committed to advancing new vaccine development candidates to address serious unmet needs.”
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