J&J inks a $1.15B discovery deal with PeptiDream; Medivir plots PhIII HDAC program
→ Tokyo-based PeptiDream has struck a discovery deal with J&J worth up to $1.15 billion. In the deal PeptiDream will use its platform tech to “identify macrocyclic/constrained peptides against multiple metabolic and cardiovascular targets of interest selected by Janssen, and to optimize hit peptides into therapeutic peptides or small molecule products.”
→ Sweden’s Medivir says that they’ve gathered some positive results from a Phase II study of their HDAC inhibitor remetinostat for cutaneous T-cell lymphoma. Early stage patients in the 1% remetinostat gel BID arm had the highest proportion of confirmed responses (8/20, 40%), including one complete response. The biotech says it is now planning a pivotal Phase III program.
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